مرجـع دانـش پارس

نوع فایل:PDF

 تعداد صفحات:7

سال انتشار:1395

چکیده

Due to biological and physicochemical properties of poly (-amino acid)s interest in synthesis of their novel derivatives was recently increased. As a new and simple approach, an aromatic poly (-amino acid), poly (AA), was prepared from poly salicylaldehyde (PSA) as a precursor which -amino acid groups formed as pendant groups on the PSA framework. PSA was prepared by a poly condensation reaction, after treatment of salicylaldehyde with chloromethylene group. Transformation of PSA to poly (AA) was done through Strecker synthesis with a cyanide salt. The final step includes hydrolysis of nitrile groups to carboxylic acid through a simple one step reaction. Poly (AA) and PSA were characterized by FTIR, 1H NMR instruments and elemental analysis. Both of PSA and poly (AA) had the melting point above 400 C. Also the number-average molecular weight (Mn) of PSA was 2190 that measured by Warly titration method where polymer was dissolved in pyridine/acetic anhydride mixture and titrated with NaOH 0.5 N as a titrant.

واژگان کلیدی

poly (-amino acid), poly (-amino nitrile), poly salicylaldehyde, poly condensation reaction, Number-average molecular weight